Associate Medical Director, Experimental Medicine, Early Clinical Development
San Rafael, CA
Who We Are From research and discovery to post-market clinical development, our WWRD engine involves all bench and clinical research and the associated groups that support those endeavors. Our teams work on developing first-in-class and best-in-class therapeutics that provide meaningful advances to patients who live with genetic diseases. BioMarin\u2019s Experimental Medicine is a group of physician-scientists that support pipeline advancement and growth of the clinical portfolio.\u00A0 As an Early Clinical Development function, our group of physician-scientists link research initiatives and technical assessments of external innovation to areas of development based on fundamental understanding of genetics, molecular mechanisms, disease phenotypes, and medical need in specific patient populations. We seek a neurology trained physician-scientist to support the early clinical development of a broad portfolio of programs in neurogenetic diseases.\u00A0RESPONSIBILITIES:Support neurogenetic programs within Experimental Medicine as a primary early clinical leadHelp design and conduct early clinical studies, from natural history through treatment proof-of-mechanism clinical trialsAuthor translational and pre-treatment plans based on research resultsInterrogate natural history and disease progression of therapeutic indication to plan a development strategy encompassing biomarkers, endpoints, and target patient populationServe as subject matter expertise\u00A0of genetically driven neurologic disease\u00A0by keeping current with literature, meetings, and disease pipelineWork collaboratively with research and clinical groups to advance programsHelp generate development plans, draft product characterization, first-in-human and proof of concept trial strategy, draft clinical development plansEarly clinical representative in investigative new drug (IND) filing teamRepresent Early Clinical Development in scientific advisory and academic meetingsIdentify high value therapeutic targets for neurogenetic indications and contribute clinical expertise to groups involved in disease mapping and pipeline strategyWork with Research, Innovation Accelerator and Business Development to facilitate clinical diligence of new development opportunitiesParticipate in scientific advisory boards convened by BioMarin to support the research initiatives in neurogeneticsQUALIFICATIONS:MD or MD/PhD requiredStrong record of academic, basic and/or translational research productivitySolid foundation and interest in mechanisms of\u00A0neurogenetic diseasesBoard certified or eligible in adult or pediatric neurologyInterest and curiosity in development challengesEffective and impactful in cross-functional team structureExcellent communication skills, with a desire to develop strong internal and external collaborations\u00A0 PLEASE NOTE: Absent a Medical or Religious reason that prohibits vaccinations, all our incoming employees must be vaccinated for COVID-19. We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity, sexual orientation, national origin, disability status, protected veteran status, or any other characteristic protected by law.
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