Intern, Gene Therapy
San Rafael, CA
Who We Are For more than two decades, going our own way has led to countless breakthroughs, bettering the lives of those suffering from rare genetic disease. In 1997 we were founded to make a big difference in small patient populations. Now we seek to make an even greater impact by applying the same science-driven, patient-forward approach that propelled our last 25 years of drug development to larger genetic disorders, as well as genetic subsets of more common conditions. Through our unparalleled expertise in genetics and molecular biology, we will continue to develop targeted therapies that address the root cause of the conditions we seek to treat. Applying our knowledge to make a transformative impact is not just a calling, but an obligation to those who will benefit most. The end goal has always been better lives and now we can reach more. And the more people we reach, the more our impact can grow. We transform lives through genetic discovery. Our Culture Our desire to make a positive impact on our patients extends to our employees and BioMarin is committed to fostering an inclusive environment where every person feels seen, valued, and heard \u2013 so employees can thrive in all areas of their lives, in and outside of work. We seek to provide an open, flexible, and friendly work environment to empower people and to provide them with the ability to develop their long-term careers. Ultimately, we want to be an organization where people enjoy coming to work and take pride in our efforts to help patients.\u00A0SUMMARY:The BioMarin Summer Internship Program will enable students to gain valuable experience and knowledge of the processes and systems within BioMarin, while gaining an insight into the pharmaceutical/biotech industry. BioMarin\u2019s Research & Development group is responsible for everything from research and discovery to post-market clinical development. Research & Development involves all bench and clinical research and the associated groups that support those endeavors. Our teams work on developing first-in-class and best-in-class therapeutics that provide meaningful advances to patients who live with rare diseases. JOB DESCRIPTION/PROJECT:The selected candidate will work in the Research Gene Therapy Group and primarily focus on assessing impact of production process on kinetics and biodistribution profile of AAV vectors. The candidate will work on the following activities with guidance from their manager: - Extract DNA/RNA from various animal tissues- Design primers and probes for qPCR, RTqPCR and ddPCR assays- Develop and execute qPCR, RT-qPCR and ddPCR assays- Maintain thorough and timely documentation of experimental protocols and findings- Prepare slides and present results at project team meetings\u00A0Required Skills: Basic lab skills Familiarity with basic molecular and cellular biology techniques Strong ability to learn new skills Excellent oral and written communication skills\u00A0Desired Skills: Familiarity with AAV gene therapy DNA/RNA extraction Primer design, ddPCR, qPCR, RT-qPCR, Western blot Immunohistochemical and in situ hybridization assays \u00A0Qualifications/Eligibility:Student working toward a B.S., M.S., or Ph.D. degree in molecular biology, genetics, biochemistry, or related disciplines.Student must be returning to school in the Fall Term OR has graduated within the 1 year of the start of the program.\u00A0 Must be available to work 40 hours a weekMust be authorized to work in the United States without visa sponsorshipBenefits of a BioMarin Internship:Apply skills and knowledge learned in the classroom to on-the-job experiencesComprehensive, value-added project(s)Work in teams and with colleagues in a professional environment.Develop skills specific to your major.Opportunities for professional development by building relationships and learning about other parts of the business.Weekly Speaker Seminar Series with Executive Staff. In the U.S., the hiring range for this position is $ 21.00 to $ 50.00 per hour. The base pay actually offered will take into account internal equity and also may vary depending on the candidate\u2019s geographic region, job-related knowledge, skills, and experience among other factors.PLEASE NOTE: Absent a Medical or Religious reason that prohibits vaccinations, all our incoming employees must be vaccinated for COVID-19.We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity, sexual orientation, national origin, disability status, protected veteran status, or any other characteristic protected by law.
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