Intern, Biconjugate Chemistry
San Rafael, CA
Who We Are For more than two decades, going our own way has led to countless breakthroughs, bettering the lives of those suffering from rare genetic disease. In 1997 we were founded to make a big difference in small patient populations. Now we seek to make an even greater impact by applying the same science-driven, patient-forward approach that propelled our last 25 years of drug development to larger genetic disorders, as well as genetic subsets of more common conditions. Through our unparalleled expertise in genetics and molecular biology, we will continue to develop targeted therapies that address the root cause of the conditions we seek to treat. Applying our knowledge to make a transformative impact is not just a calling, but an obligation to those who will benefit most. The end goal has always been better lives and now we can reach more. And the more people we reach, the more our impact can grow. We transform lives through genetic discovery. Our Culture Our desire to make a positive impact on our patients extends to our employees and BioMarin is committed to fostering an inclusive environment where every person feels seen, valued, and heard \u2013 so employees can thrive in all areas of their lives, in and outside of work. We seek to provide an open, flexible, and friendly work environment to empower people and to provide them with the ability to develop their long-term careers. Ultimately, we want to be an organization where people enjoy coming to work and take pride in our efforts to help patients.\u00A0SUMMARY:The BioMarin Summer Internship Program will enable students to gain valuable experience and knowledge of the processes and systems within BioMarin, while gaining an insight into the pharmaceutical/biotech industry. We are seeking a highly motivated and promising chemist to join the Delivery Group within the Research Department at BioMarin Pharmaceutical, Inc. We are looking for a candidate to synthesize and build polymer-based bioconjugates for targeted drug delivery of peptides and oligonucleotides. With a growing track record of success and strong interest in bioconjugations, the candidate must have some prior experience in organic chemistry and be able to think analytically & problem solve with synthetic chemistry. This position offers a unique career opportunity to contribute to exploratory programs in gene delivery research that will sharpen the candidate\u2019s chemistry and drug delivery expertise and learn to tackle biology-focused problems with a chemistry mindset. Working at the interface of various therapeutic modalities, the candidate will be exposed to new thinking, perspectives, and delivery solutions to treat rare genetic diseases.\u00A0\u00A0 \u00A0JOB DESCRIPTION/PROJECT:This intern role will partner closely with research team members in CNS and/or Musculoskeletal therapeutic areas to deep dive on one or more bioconjugation chemistries for early exploratory projects. The successful candidate will contribute to projects by developing and optimizing new polymer-based bioconjugations for oligonucleotide and/or peptide drug delivery. They will also need to maintain a high degree of curiosity and a strong desire for continuous learning.\u00A0Required Skills: Minimum of 0-1 year of synthetic or organic chemistry lab experience Working technical knowledge or bench-experience with bioanalytical techniques such as but not limited to chromatography, spectrophotometry, gel electrophoresis, and particle analyzer Willingness and self-motivation to learn new synthetic chemistry Ability to follow protocols and perform experiments under supervisory directions The position requires organization skills, attention to detail, and strong teamwork in a fast-paced settingDesired Skills: Chemistry experienced focused on conjugation of biomolecules and bioconjugation reactions; ability to optimize or troubleshoot in organic chemistry Chromatographic purification experience of bioconjugates with the ability to develop/implement analytics for QC A developing background or interest in drug delivery Qualifications/Eligibility: Student in their 3rd or 4th year pursuing a Bachelor\u2019s degree -OR- those pursuing a Master\u2019s degree in organic chemistry, biochemistry, bioengineering, chemical biology, molecular biology, or related field Student must be returning to school in the Fall Term OR has graduated within the 1 year of the start of the program. Must be available to work 40 hours a week Must be authorized to work in the United States without visa sponsorshipBenefits of a BioMarin Internship:Apply skills and knowledge learned in the classroom to on-the-job experiencesComprehensive, value-added project(s)Work in teams and with colleagues in a professional environment.Develop skills specific to your major.Opportunities for professional development by building relationships and learning about other parts of the business.Weekly Speaker Seminar Series with Executive Staff. In the U.S., the hiring range for this position is $ 21.00 to $ 30.00 per hour. The base pay actually offered will take into account internal equity and also may vary depending on the candidate\u2019s geographic region, job-related knowledge, skills, and experience among other factors.PLEASE NOTE: Absent a Medical or Religious reason that prohibits vaccinations, all our incoming employees must be vaccinated for COVID-19.We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity, sexual orientation, national origin, disability status, protected veteran status, or any other characteristic protected by law.
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